Yasmin Granot-Matok
PhD Candidate, MRNA Delivery And Cancer Research
Or-Aqiva
Summary
Dedicated candidate eager to put analytical and problem-solving skills to practice in professional setting. Skilled at gathering and analyzing data for research with keen eye for accuracy. Organized and successful at managing multiple priorities with a positive attitude. Flexible with solid adaptability for working in dynamic environment. Currently at the final stages of writing her PhD thesis dealing with developing an mRNA-based therapy for the treatment of solid tumors.
Overview
8
8
years of professional experience
10
10
years of post-secondary education
Work History
Research Associate
NanoGhost
11.2022 - 05.2023
Developing an assay for mRNA quantification in stem cell-based nanoparticles.
Teacher, Immunology Lab Course
Life Sciences Faculty, Tel-Aviv University
10.2016 - 10.2018
Recipient of the Faculty Teaching Award for 2016-2017 academic year.
Student Position
BioPlan
07.2015 - 08.2015
A summer work assisting Regulatory affairs submissions to the MOH.
Education
Ph.D. - Nanotechnology And Cancer Research
Tel-Aviv University
10.2016 - Current
Bachelor of Science - Biotechnology
Tel-Aviv University
10.2012 - 09.2015
Skills
Literature review, scientific writing and presentation
Cell culture and culture-based assays (luciferase reporter expression, XTT)
LNPs formulation and production
In-vitro transcription (mRNA synthesis)
Molecular biology: cloning, PCR, DNA purification
Immunological-based assays: FACS, ELISA
In-vivo solid tumors models, ex-vivo tissue and single-cell suspension isolation
Targeted LNPs delivery
Publications
Granot-Matok Y, Ezra A, Ramishetti S, Sharma P, Naidu GS, Benhar I, Peer D. Lipid nanoparticles-loaded with toxin mRNA represents a new strategy for the treatment of solid tumors. Theranostics. 2023 Jun 12;13(11):3497-3508
Granot-Matok Y, Kon E, Dammes N, Mechtinger G, Peer D. Therapeutic mRNA delivery to leukocytes. J Control Release. 2019
Veiga, N., Goldsmith, M., Granot, Y. et al. Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes. Nat Commun 9, 4493 (2018).
Granot Y, Peer D. Delivering the right message: Challenges and opportunities in lipid nanoparticles-mediated modified mRNA therapeutics-An innate immune system standpoint. Semin Immunol. 2017
Timeline
Research Associate
NanoGhost
11.2022 - 05.2023
Teacher, Immunology Lab Course
Life Sciences Faculty, Tel-Aviv University
10.2016 - 10.2018
Ph.D. - Nanotechnology And Cancer Research
Tel-Aviv University
10.2016 - Current
Student Position
BioPlan
07.2015 - 08.2015
Bachelor of Science - Biotechnology
Tel-Aviv University
10.2012 - 09.2015