TOMA TOMOV
Ramat Gan,TA
Summary
As a dedicated and independent scientist, I boast a track record of achievements in leadership, rigorous research, and communication. With over 10 years of practical experience, I have cultivated a deep proficiency in experimental design, method development, data analysis, and DNA nanotechnology. I have a proven ability to work effectively in a multidisciplinary environment, both individually and as part of a team, and have consistently managed multiple projects and deadlines simultaneously. My reputation for creative problem-solving and scientific innovation, coupled with my significant contributions to research improvements, are hallmarks of my career. I offer comprehensive practical knowledge in molecular biology, nanotechnology, microscopy, and microfluidic fabrication.
Overview
14
14
years of professional experience
Work History
Senior Application Scientist
Picodya technologies LTD.
01.2021 - Current
- Head of the molecular assay development team
- Development of molecular detection assays for pathogens on Picodya’s point of care platform
- Exploring various multiplexed molecular amplification methods
- Development of fast RNA and DNA extraction assays for POC diagnostics from saliva, blood, and urine
- Development of micro-RNA detection assay for cancer diagnostics
- Working with teams towards FDA submissions.
Postdoctoral Researcher
Wyss Institute for Biologically Inspired Engineering | Harvard University
01.2016 - 01.2021
- Single molecule force spectroscopy applications for high throughput protein characterization
- Establishment of fast-fluid-exchange microfluidic system and covalent surface functionalization of force measurements
- Platform design and fabrication of magnetic tweezer microscope for high throughput measurements of single molecule
- Single molecule protein finger printing, sequencing, and identification
- Authoring scientific publication under revision of Nature Nanotechnology
- Assistance in grant, manuscript, and fellowship preparation.
Junior Faculty Staff
Ben Gurion University of the Negev
01.2010 - 01.2016
- Lab instructor in Physical Chemistry.
Lab Assistant
Ben Gurion University of the Negev
- Assisting in the synthesis of new click chemistry catalyzer.
Education
Ph.D. - Biophysics and Nanotechnology
Ben Gurion University of the Negev
01.2016
M.Sc. - Biophysics and Nanotechnology
Ben Gurion University of the Negev
01.2011
B.Sc. - Chemistry
Ben Gurion University of the Negev
01.2009
Skills
- Solving tough problems
- Creative thinking
- Scientific innovation
- Team collaboration and communication
- Cultivating talent
- Analytical approach
- Molecular biology - isothermal amplification, DNA/RNA extraction, PCR, and qPCR
- Structural DNA Nanotechnology - conceive, design, and synthesize of DNA-based nanostructures using synthetic oligonucleotides, chemical synthesis and developing protocols for DNA object assembly
- Microfluidics - lithography design and fabrication, multi-layer soft lithography and surface functionalization, high precision photo-lithography
- Microscopy - design and development of force microscopy, single molecule fluorescent microscopy, total internal reflection fluorescent (TIRF) microscopy
- Computer Skills - LabView, OriginLab, MatLab, CorelDraw, AutoCAD, ChemDraw, Pymol, Molecular Operating Environment, EndNote, Microsoft suite of products, Adobe Illustrator and Photoshop
Publications
- Single-molecule mechanical fingerprinting with DNA nanoswitch calipers, P Shrestha, D Yang, TE Tomov, JI MacDonald, A Ward, HT Bergal, E Krieg, S Cabi, Y Luo, B Nathwani, A Johnson-Buck, WM Shih, and WP Wong, Nature nanotechnology, 16, 12, 1362-1370, 2021
- DNA bipedal motor achieves a large number of steps due to operation using microfluidics-based interface, TE Tomov, R Tsukanov, Y Glick, Y Berger, M Liber, D Avrahami, D Gerber, and E Nir, ACS nano, 11, 4, 4002-4008, 2017
- Disentangling subpopulations in single-molecule FRET and ALEX experiments with photon distribution analysis, TE Tomov, R Tsukanov, R Masoud, M Liber, N Plavner, and E Nir, Biophysical journal, 102, 5, 1163-1173, 2012
- Rational design of DNA motors: fuel optimization through single-molecule fluorescence, TE Tomov, R Tsukanov, M Liber, R Masoud, N Plavner, and E Nir, Journal of the American Chemical Society, 135, 32, 11935-11941, 2013
Languages
- Hebrew - native
- Bulgarian - native
- English - fluent
- French - beginner
Timeline
Senior Application Scientist
Picodya technologies LTD.
01.2021 - Current
Postdoctoral Researcher
Wyss Institute for Biologically Inspired Engineering | Harvard University
01.2016 - 01.2021
Junior Faculty Staff
Ben Gurion University of the Negev
01.2010 - 01.2016
Lab Assistant
Ben Gurion University of the Negev
Ph.D. - Biophysics and Nanotechnology
Ben Gurion University of the Negev
M.Sc. - Biophysics and Nanotechnology
Ben Gurion University of the Negev
B.Sc. - Chemistry
Ben Gurion University of the Negev
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